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| Registros recuperados : 316 | |
| 21. |  | TIERI, M.; LA MANNA, A.; BANCHERO, G.; MIERES, J.; FERNANDEZ, E.; INVERNIZZI, G.; BUFFA, I.; MONTOSSI, F. Balances de nitrógeno y fósforo en sistemas ganaderos del Uruguay // Nutrient balances of nitrogen and phosphorus in livestock production systems in Uruguay. Revista Argentina de Producción Animal, v. 32, suppl. 1, p. 78, 2012. In: CONGRESO ARGENTINO DE PRODUCCIÓN ANIMAL, 35. 2012. Resúmenes. Córdoba, AR: AAPA, 2012. SP 58.| Biblioteca(s): INIA La Estanzuela; INIA Tacuarembó. |
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| 23. | | LA MANNA, A. Cadena láctea. [Exposición oficial en representación de Pablo Chilibroste] In: JORNADAS OSCAR MAGGIOLO, 2005, MONTEVIDEO, UY. Conocimiento y cadenas productivas. Montevideo, UY: UdelaR, 2006. 165 p. (Documento de Trabajo del Rectorado, 29). p.97. (Documento de Trabajo del Rectorado, 29). Cadena láctea: [segunda jornada, 1 dic 2005] / moderador: Roberto Kremer; expositores del sector productivo: Carlos Mattos, Jorge Marzaroli; expositor del INIA: Alejandro La Manna; expositores de la UdelaR: Jorge Álvarez, Patricia Lema.| Biblioteca(s): INIA La Estanzuela. |
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| 24. | | CIGANDA, V.; LA MANNA, A. Calidad de agua de escurrimiento de un feedlot experimental en Uruguay. In: CONGRESO ARGENTINO DE PRODUCCIÓN ANIMAL, 34.; JOINT MEETING AAPA-ASAS, 1., 2011, Mar del Plata. Resúmenes. Mar del Plata: ASAS/AAPA, 2011. Revista Argentina de Producción Animal, v. 31, suppl.1. p. 256, 2011.| Biblioteca(s): INIA La Estanzuela. |
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| 27. | | MORON, A.; MOLFINO, J.; SAWCHIK, J.; CALIFRA, A.; LAZBAL, E.; LA MANNA, A.; MALCUORI, E. Calidad del suelo en las principales áreas de producción lechera de Uruguay: avances en el Departamento de Colonia In: Jornada Técnica calidad de suelos. La Estanzuela, Colonia, Uruguay: INIA, 2008. p. 9-13. (INIA Serie Actividades de Difusión; 556).| Biblioteca(s): INIA La Estanzuela. |
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| 28. | | MORON, A.; SAWCHIK, J.; CALIFRA, A.; LAZBAL, E.; IBAÑEZ, W.; LA MANNA, A.; MALCUORI, E. Calidad del suelo en las principales áreas de producción lechera de Uruguay: avances en el Departamento de Florida. In: Jornada Técnica calidad de suelos. La Estanzuela, Colonia, Uruguay: INIA, 2008. p.1-6. (INIA Serie Actividades de Difusión; 556).| Biblioteca(s): INIA La Estanzuela. |
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| 29. | | LEMA, O.M.; BRITO, G.; CLARIGET, J.; PEREZ, E.; LA MANNA, A.; RAVAGNOLO, O.; AGUILAR, I.; MONTOSSI, F. Can nutritional level and parental EPD for rib eye area influence feed conversion efficiency and carcass yield in steers?.[Poster]. In: AUSTRALIAN SOCIETY OF ANIMAL PRODUCTION; NEW ZEALAND SOCIETY OF ANIMAL PRODUCTION, 31st,2016. Proceedings. Adelaida, South Australia, AU: ASAP. 2016.| Biblioteca(s): INIA La Estanzuela. |
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| 39. | | MONTOSSI, F.; SAN JULIÁN, R.; BRITO, G.; VAZ MARTINS, D.; LUZARDO, S.; DEL CAMPO, M.; FERNANDEZ, E.; HELGUERA, L.; LA MANNA, A.; DE BARBIERI, I.; NOLLA, M.; MESSA, A.; VON ACHENBACH, A.; CASTRO, L.; ROBAINA, R. Conociendo la aceptación de nuestras carnes ovinas y bovinas en Europa Revista INIA, 2005, no. 5, p. 47-48| Biblioteca(s): INIA La Estanzuela; INIA Las Brujas; INIA Tacuarembó. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha actual : |
15/04/2021 |
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Actualizado : |
15/04/2021 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
COSTA, D.; LÉVESQUE, S.; KUMAR, N.; FRESIA, P.; FERRÉS, I.; LAWLEY, T. D.; IRAOLA, G. |
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Afiliación : |
DANIELA COSTA, Microbial Genomics Laboratory, Institut Pasteur Montevideo, Montevideo, Uruguay; Sección Genética Evolutiva, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay; SIMON LÉVESQUE, Laboratoire de Santé Publique du Québec, Quebec City, Canada; NITIN KUMAR, Wellcome Sanger Institute, Hinxton, Cambridgeshire, UK; PABLO FRESIA, Unidad Mixta UMPI, Institut Pasteur Montevideo + INIA, Montevideo, Uruguay; IGNACIO FERRÉS, Microbial Genomics Laboratory, Institut Pasteur Montevideo, Montevideo, Uruguay; TREVOR D. LAWLEY, Wellcome Sanger Institute, Hinxton, Cambridgeshire, UK; GREGORIO IRAOLA, Microbial Genomics Laboratory, Institut Pasteur Montevideo, Montevideo, Uruguay; Wellcome Sanger Institute, Hinxton, Cambridgeshire, UK; Center for Integrative Biology, Universidad Mayor, Santiago de Chile, Chile. |
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Título : |
Pangenome analysis reveals genetic isolation in Campylobacter hyointestinalis subspecies adapted to different mammalian hosts. |
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Fecha de publicación : |
2021 |
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Fuente / Imprenta : |
Scientific Reports, 2021, Volume 11, Issue 1, Article number 3431. OPEN ACCESS. Doi: https://doi.org/10.1038/s41598-021-82993-9 |
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ISSN : |
2045-2322 |
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DOI : |
10.1038/s41598-021-82993-9 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 12 February 2018; Accepted 24 January 2021; Published 09 February 2021. |
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Contenido : |
ABSTRACT.
Campylobacter hyointestinalis is an emerging pathogen currently divided in two subspecies: C. hyointestinalis subsp. lawsonii which is predominantly recovered from pigs, and C. hyointestinalis subsp. hyointestinalis which can be found in a much wider range of mammalian hosts. Despite C. hyointestinalis being reported as an emerging pathogen, its evolutionary and host-associated diversification patterns are still vastly unexplored. For this reason, we generated whole-genome sequences of 13 C. hyointestinalis subsp. hyointestinalis strains and performed a comprehensive comparative analysis including publicly available C. hyointestinalis subsp. hyointestinalis and C. hyointestinalis subsp. lawsonii genomes, to gain insight into the genomic variation of these differentially-adapted subspecies. Both subspecies are distinct phylogenetic lineages which present an apparent barrier to homologous recombination, suggesting genetic isolation. This is further supported by accessory gene patterns that recapitulate the core genome phylogeny. Additionally, C. hyointestinalis subsp. hyointestinalis presents a bigger and more diverse accessory genome, which probably reflects its capacity to colonize different mammalian hosts unlike C. hyointestinalis subsp. lawsonii that is presumably host-restricted. This greater plasticity in the accessory genome of C. hyointestinalis subsp. hyointestinalis correlates to a higher incidence of genome-wide recombination events, that may be the underlying mechanism driving its diversification. Concordantly, both subspecies present distinct patterns of gene families involved in genome plasticity and DNA repair like CRISPR-associated proteins and restriction-modification systems. Together, our results provide an overview of the genetic mechanisms shaping the genomes of C. hyointestinalis subspecies, contributing to understand the biology of Campylobacter species that are increasingly recognized as emerging pathogens.
© 2021, The Author(s). MenosABSTRACT.
Campylobacter hyointestinalis is an emerging pathogen currently divided in two subspecies: C. hyointestinalis subsp. lawsonii which is predominantly recovered from pigs, and C. hyointestinalis subsp. hyointestinalis which can be found in a much wider range of mammalian hosts. Despite C. hyointestinalis being reported as an emerging pathogen, its evolutionary and host-associated diversification patterns are still vastly unexplored. For this reason, we generated whole-genome sequences of 13 C. hyointestinalis subsp. hyointestinalis strains and performed a comprehensive comparative analysis including publicly available C. hyointestinalis subsp. hyointestinalis and C. hyointestinalis subsp. lawsonii genomes, to gain insight into the genomic variation of these differentially-adapted subspecies. Both subspecies are distinct phylogenetic lineages which present an apparent barrier to homologous recombination, suggesting genetic isolation. This is further supported by accessory gene patterns that recapitulate the core genome phylogeny. Additionally, C. hyointestinalis subsp. hyointestinalis presents a bigger and more diverse accessory genome, which probably reflects its capacity to colonize different mammalian hosts unlike C. hyointestinalis subsp. lawsonii that is presumably host-restricted. This greater plasticity in the accessory genome of C. hyointestinalis subsp. hyointestinalis correlates to a higher incidence of genome-wide recombination events, that may be the under... Presentar Todo |
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Palabras claves : |
Computational biology and bioinformatics; Evolution; Microbiology. |
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Asunto categoría : |
A50 Investigación agraria |
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URL : |
https://www.nature.com/articles/s41598-021-82993-9.pdf
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Marc : |
LEADER 02962naa a2200265 a 4500
001 1061986
005 2021-04-15
008 2021 bl uuuu u00u1 u #d
022 $a2045-2322
024 7 $a10.1038/s41598-021-82993-9$2DOI
100 1 $aCOSTA, D.
245 $aPangenome analysis reveals genetic isolation in Campylobacter hyointestinalis subspecies adapted to different mammalian hosts.$h[electronic resource]
260 $c2021
500 $aArticle history: Received 12 February 2018; Accepted 24 January 2021; Published 09 February 2021.
520 $aABSTRACT. Campylobacter hyointestinalis is an emerging pathogen currently divided in two subspecies: C. hyointestinalis subsp. lawsonii which is predominantly recovered from pigs, and C. hyointestinalis subsp. hyointestinalis which can be found in a much wider range of mammalian hosts. Despite C. hyointestinalis being reported as an emerging pathogen, its evolutionary and host-associated diversification patterns are still vastly unexplored. For this reason, we generated whole-genome sequences of 13 C. hyointestinalis subsp. hyointestinalis strains and performed a comprehensive comparative analysis including publicly available C. hyointestinalis subsp. hyointestinalis and C. hyointestinalis subsp. lawsonii genomes, to gain insight into the genomic variation of these differentially-adapted subspecies. Both subspecies are distinct phylogenetic lineages which present an apparent barrier to homologous recombination, suggesting genetic isolation. This is further supported by accessory gene patterns that recapitulate the core genome phylogeny. Additionally, C. hyointestinalis subsp. hyointestinalis presents a bigger and more diverse accessory genome, which probably reflects its capacity to colonize different mammalian hosts unlike C. hyointestinalis subsp. lawsonii that is presumably host-restricted. This greater plasticity in the accessory genome of C. hyointestinalis subsp. hyointestinalis correlates to a higher incidence of genome-wide recombination events, that may be the underlying mechanism driving its diversification. Concordantly, both subspecies present distinct patterns of gene families involved in genome plasticity and DNA repair like CRISPR-associated proteins and restriction-modification systems. Together, our results provide an overview of the genetic mechanisms shaping the genomes of C. hyointestinalis subspecies, contributing to understand the biology of Campylobacter species that are increasingly recognized as emerging pathogens. © 2021, The Author(s).
653 $aComputational biology and bioinformatics
653 $aEvolution
653 $aMicrobiology
700 1 $aLÉVESQUE, S.
700 1 $aKUMAR, N.
700 1 $aFRESIA, P.
700 1 $aFERRÉS, I.
700 1 $aLAWLEY, T. D.
700 1 $aIRAOLA, G.
773 $tScientific Reports, 2021, Volume 11, Issue 1, Article number 3431. OPEN ACCESS. Doi: https://doi.org/10.1038/s41598-021-82993-9
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